Is CBD Isolate Water Soluble? – CBD Isolate Solubility Explained

A bottle of CBD isolate powder laying on its side with some pouring out and a chalkboard with the CBD molecule drawn on it.

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Is CBD Isolate water soluble? The answer may change the entire way you consume your CBD. That’s why we’ve taken the time to outline the answer, and the options, in this article.

While CBD in its original form is oily and thus not water soluble, it can be processed to become water soluble. CBD isolate is commonly sold in three main forms (oil, powder, and crystals). CBD oil is not water soluble, but CBD isolate powder and CBD isolate crystals are water soluble. So, if you purchase CBD isolate in the form of powder or crystals then, yes, you can effectively mix it with water and still reap its benefits.

However, CBD isolate comes in many forms, and water soluble CBD comes in many forms, and the answer to your question varies slightly depending on what form you plan on using. For that reason, read on for a more in-depth look at the answer to the question, “Is CBD isolate water soluble?

Is CBD Isolate Water Soluble?

To answer this question fully, let’s break it down according to the three main types of CBD isolate:

  1. Powder
  2. Crystals
  3. Oil

CBD isolate in its natural form is an oily substance and cannot be mixed with water. But it can be treated so that it becomes water soluble.

Is CBD isolate powder water soluble?

For the most part, yes, you can mix CBD isolate powder with water or even hot drinks and most of it will properly dissolve, giving you the effects of CBD. While it may not be 100%, you should still be able to consume CBD isolate powder when mixed with a liquid.

Are CBD isolate crystals water soluble?

Yes, CBD isolate crystals can be mixed with food and beverages. The crystals dissolve quite easily in drinks.

Is CBD isolate oil water soluble?

Oil and water don’t mix, so while you could put a few drops of CBD oil into your morning coffee, the drops may sit on top or stick to the sides of the glass. The most effective form of consuming CBD oil will probably be administering a few drops under the tongue.

CBD Isolate Solubility

Technically, oily substances like CBD can never break down and completely mix with water. Because CBD isolate is pure CBD, that means it is in its pure, natural form, which is oily. To get around this, scientists use nano-emulsions, which break down the CBD into tiny particles allowing it to more easily mix into liquids.

That means that while, on a molecular level, the CBD is not completely dissolving like sugar and salt, it still appears to be water soluble, and it is evenly distributed throughout your drink. Thus, you can ingest all the CBD that you put in your drink or food, and therefore enjoy its benefits.

By making the CBD appear water soluble, the bioavailability of the CBD isolate becomes higher, AKA, more of the CBD gets absorbed into your bloodstream. Why? The human body is mostly water. So if you purchase CBD isolate in its powder or crystal form, you can enjoy a product with higher bioavailability.

A glass of water mixed with water soluble CBD to the left and a glass of water with traditional CBD oil floating on the top to the right.

How do you dissolve CBD isolate?

The main difference between water soluble CBD oils and conventional CBD oils is a process called nanoemulsion. Nanoemulsion is the process used to help dissolve CBD isolate or other CBD oils into water.

Nanoemulsion involves breaking down CBD oil into tiny particles that can be manipulated. These particles, which usually create the oily substance we’re all familiar with, are naturally hydrophobic, meaning they repel water. This is the main reason that conventional CBD isolate has a low bioavailability.

However, when reduced to particles, CBD isolate has the ability to change almost completely. Nanoemulsion allows these particles to be distributed throughout a substance, in this case water, which it would not normally bind to.

Instead of being repelled by water and therefore failing to mix with and break down in it, CBD particles that have undergone nanoemulsion can actually be dispersed throughout the rest of the solution, almost as if it’s been mixed together at the molecular level.

So, to summarize: in order to create a water soluble CBD product, CBD isolate or CBD oil must be broken down into small particles via nanoemulsion. These small particles are dispersed throughout water (sometimes with the help of additional molecules) and are broken down more easily in water. This means that water soluble CBD has a higher bioavailability and is more efficiently processed in the body.

For more information regarding nanoemulsion and water soluble CBD, check out this related reading. Though it’s a topic we’ve explored before, it’s hard to stress the genuine importance of water soluble CBD. For many in the cannabis world, including us here at CBD Facilitator, water soluble CBD is truly a game changer.

It’s likely that the process will be used increasingly over time as cannabis use in general continues to spike. Who knows what sort of other scientific discoveries we can utilize to make our experiences even better?

Dissolving CBD Isolate Step by Step

To further break down and understand the process of creating water soluble CBD, it can be helpful to look at things chronologically. To keep things simple, you can continue to visualize how oil and water tend to separate – in this case, CBD is the oil that refuses to dissolve fully into water.

Making water soluble CBD products is no easy task, and is usually done with the help of specific technology and methods, so you can’t simply buy CBD Isolate then make it into water soluble CBD at home. Your best method for getting water soluble CBD would be to purchase it in its already soluble form. 

The first step is, of course, to obtain CBD isolate or CBD oil. These products represent CBD in its most natural and pure form, but they don’t mix well with water. In fact, their molecules quite literally repel water. So, the nanoemulsion process begins.

The process begins by dissolving CBD isolate. Once it’s in a liquid, oily form, CBD can be broken down into small particles via high amounts of pressure. Emulsifiers, substances that help stabilize the mixture, may also come into play.

Once CBD has been broken down into particles, it can be distributed throughout water. This is where the presence of emulsifiers can really be key – oils and waters don’t like to mix, even at the molecular level.

The result of this process is a potent, efficient product that absorbs much better into the bloodstream and produces much stronger effects. It’s not as simple as creating and selling conventional CBD oil or isolate is, but it certainly does the job much better.

If you’re trying out water soluble CBD for the first time, you may want to exercise some caution when selecting a dose. The process outlined above makes a big difference in terms of how your body will process the CBD you consume, and it may be a different experience than what you’re used to.

Can you put CBD isolate in tea/drinks?

You can, but how many of the benefits you get will depend on the form it’s in.

If you put CBD isolate oil into your coffee, for example, then the oil may not mix with the water and it can create a sort of film on the bottom of the cup instead of going into your system.

But if you have powder, or better yet, CBD isolate designed to be water soluble, then you can absolutely put it into your teas and other drinks and it will all be absorbed.

CBD isolate is a great option for many people because it lacks a lot of the things that can make other forms of CBD consumption unpleasant – like a strong taste from your product, for example, or a strong smell.

Because CBD isolate is purely CBD – no other cannabinoids or parts of the cannabis plant – it is usually odorless, tasteless, and therefore easy to incorporate into your life in a variety of ways. Many CBD isolate products come in a powder form, so they’re great additives to just about anything you consume, including food or drinks.

CBD isolate is a great choice if you want to be sure you’re only consuming CBD and nothing else. If CBD isolate works out well for you, water soluble CBD may also be a great option, as discussed above.

You can still reap the benefits of CBD isolate even when it’s been made into a water soluble product. In fact, you’ll likely be reaping even more benefits than you would be otherwise thanks to nanoemulsion!


CBD isolate in oil form is not water soluble, so if you plan on consuming your CBD in water, we recommend directly purchasing water soluble CBD.

Here at CBD Facilitator, we’ve made it our mission to provide comprehensive education about all types of cannabis and cannabis derivatives, including CBD isolate. Fortunately for CBD users, the introduction of water soluble options make it even easier to get effective doses of product with maximum absorption.

The process that creates water soluble CBD isn’t necessarily as complicated as it may seem. Emulsion is a common practice across all sorts of fields, and taking advantage of its ability to combine things that wouldn’t otherwise work out – oil and water, most frequently – means more powerful medicine for all.

If you’re interested in purchasing water soluble CBD for yourself, be sure to check out our directory for product recommendations. If you’re a fan of CBD isolate, it’s likely you’ll be even more of a fan of water soluble options!

If you’re specifically looking for CBD isolate, click here for our personal favorite product, CBDistillery CBD Isolate Powder.

Josh Murdoch

Josh Murdoch

I was born with Cystic Fibrosis, and although it is incurable, CBD and THC have been allowing me to live my life as a healthy adult now for years. For that reason, I’ve dedicated my career to spreading the good news about cannabinoids. Currently, I work for a vertically integrated cannabis company called Unrivaled Brands that operates in California, Oregon, and Nevada. Previously, I worked on two cannabis farms in northern California, one of which was located in the famous Humboldt County. I’ve also managed a medical cannabis delivery service in Marin County, California. I created CBD Facilitator to share what I’ve learned, and to recommend the best products that I have found in this chaotic market.

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